Mouse Ralgds activation kit by CRISPRa

CAT#: GA203630

Ralgds CRISPRa kit - CRISPR gene activation of mouse ral guanine nucleotide dissociation stimulator

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Ralgds
• Locus ID: 19730
• Kit Components:

  GA203630G1, Ralgds gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA203630G2, Ralgds gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA203630G3, Ralgds gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145834, NM_001145835, NM_001145836, NM_009058
• UniProt ID: Q03385
• Synonyms: Gnds; mKIAA1308; Rgds
• Summary: Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap.[UniProtKB/Swiss-Prot Function]