Mouse Rfxank activation kit by CRISPRa

CAT#: GA203628

Rfxank CRISPRa kit - CRISPR gene activation of mouse regulatory factor X-associated ankyrin-containing protein

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Rfxank
• Locus ID: 19727
• Kit Components:

  GA203628G1, Rfxank gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA203628G2, Rfxank gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA203628G3, Rfxank gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025589, NM_011266
• UniProt ID: Q9Z205
• Synonyms: Tvl1
• Summary: Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters (By similarity). May also potentiate the activation of RAF1 (PubMed:10329666).[UniProtKB/Swiss-Prot Function]