Mouse Glud1 activation kit by CRISPRa

CAT#: GA201640

Glud1 CRISPRa kit - CRISPR gene activation of mouse glutamate dehydrogenase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Glud1
• Locus ID: 14661
• Kit Components:

  GA201640G1, Glud1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201640G2, Glud1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201640G3, Glud1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008133
• UniProt ID: P26443
• Synonyms: AI118167; Gdh-X; Glud; Gludl
• Summary: Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate.[UniProtKB/Swiss-Prot Function]