Mouse Epx activation kit by CRISPRa

CAT#: GA201278

Epx CRISPRa kit - CRISPR gene activation of mouse eosinophil peroxidase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Epx
• Locus ID: 13861
• Kit Components:

  GA201278G1, Epx gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201278G2, Epx gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201278G3, Epx gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007946
• UniProt ID: P49290
• Synonyms: EPO
• Summary: This gene encodes a member of the peroxidase superfamily of enzymes that is produced by eosinophils and plays a critical role in eliminating tissue-invasive parasites. The encoded preproprotein undergoes proteolytic processing to generate a heterodimeric enzyme that forms a predominant component of the intracellular granules of eosinophils. Mice lacking the encoded protein exhibit resistance to ulcerative colitis induced by dextran sulfate. [provided by RefSeq, Jul 2016]