Mouse Cry2 activation kit by CRISPRa

CAT#: GA200893

Cry2 CRISPRa kit - CRISPR gene activation of mouse cryptochrome 2 (photolyase-like)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Cry2
• Locus ID: 12953
• Kit Components:

  GA200893G1, Cry2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200893G2, Cry2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200893G3, Cry2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001113333, NM_009963
• UniProt ID: Q9R194
• Synonyms: AV006279; D130054K12Rik
• Summary: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. [provided by RefSeq, Feb 2014]