Mouse Cdk6 activation kit by CRISPRa

CAT#: GA200674

Cdk6 CRISPRa kit - CRISPR gene activation of mouse cyclin-dependent kinase 6

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Cdk6
• Locus ID: 12571
• Kit Components:

  GA200674G1, Cdk6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200674G2, Cdk6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200674G3, Cdk6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009873
• UniProt ID: Q64261
• Synonyms: AI504062; Crk2
• Summary: This gene encodes a member of the cyclin dependent kinase family of proteins that play important roles in the progression and regulation of the cell cycle. The encoded protein binds to a D-type cyclin to form an active kinase complex to regulate progression through the G1 phase of the cell cycle. Mice lacking the encoded protein exhibit thymic and splenic hypoplasia, and hematopoietic defects such as reduced number of megakaryocytes and erythrocytes. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2015]