Human ACSF3 activation kit by CRISPRa

CAT#: GA116299

ACSF3 CRISPRa kit - CRISPR gene activation of human acyl-CoA synthetase family member 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ACSF3
• Locus ID: 197322
• Kit Components:

  GA116299G1, ACSF3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116299G2, ACSF3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116299G3, ACSF3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127214, NM_001243279, NM_001284316, NM_174917, NR_023316, NR_045666, NR_045667, NR_104293, NR_147928, NR_147929
• UniProt ID: Q4G176
• Synonyms: FLJ39242
• Summary: This gene encodes a member of the acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for malonate and methylmalonate and possesses malonyl-CoA synthetase activity. Mutations in this gene are a cause of combined malonic and methylmalonic aciduria. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Sep 2013]