Human PLA2G2D activation kit by CRISPRa

CAT#: GA108841

PLA2G2D CRISPRa kit - CRISPR gene activation of human phospholipase A2 group IID

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PLA2G2D
• Locus ID: 26279
• Kit Components:

  GA108841G1, PLA2G2D gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108841G2, PLA2G2D gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108841G3, PLA2G2D gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271814, NM_012400
• UniProt ID: Q9UNK4
• Synonyms: PLA2IID; sPLA2-IID; sPLA2S; SPLASH
• Summary: This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]