Human PTGR1 activation kit by CRISPRa

CAT#: GA107933

PTGR1 CRISPRa kit - CRISPR gene activation of human prostaglandin reductase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PTGR1
• Locus ID: 22949
• Kit Components:

  GA107933G1, PTGR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107933G2, PTGR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107933G3, PTGR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001146108, NM_001146109, NM_012212
• UniProt ID: Q14914
• Synonyms: LTB4DH; PGR1; ZADH3
• Summary: This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]