Human UQCRFS1 activation kit by CRISPRa

CAT#: GA105090

UQCRFS1 CRISPRa kit - CRISPR gene activation of human ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: UQCRFS1
• Locus ID: 7386
• Kit Components:

  GA105090G1, UQCRFS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105090G2, UQCRFS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105090G3, UQCRFS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006003
• UniProt ID: P47985
• Synonyms: RIP1; RIS1; RISP; UQCR5
• Summary: Cytochrome b-c1 complex subunit Rieske, mitochondrial: Component of the mitochondrial ubiquinol-cytochrome c reductase complex dimer (complex III dimer), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (PubMed:28673544). Incorporation of UQCRFS1 is the penultimate step in complex III assembly (PubMed:28673544).[UniProtKB/Swiss-Prot Function]