Human Syndecan 2 (SDC2) activation kit by CRISPRa

CAT#: GA104339

SDC2 CRISPRa kit - CRISPR gene activation of human syndecan 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SDC2
• Locus ID: 6383
• Kit Components:

  GA104339G1, Syndecan 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104339G2, Syndecan 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104339G3, Syndecan 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002998
• UniProt ID: P34741
• Synonyms: CD362; HSPG; HSPG1; SYND2
• Summary: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]