Human MC4 Receptor (MC4R) activation kit by CRISPRa

CAT#: GA102837

MC4R CRISPRa kit - CRISPR gene activation of human melanocortin 4 receptor

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MC4R
• Locus ID: 4160
• Kit Components:

  GA102837G1, MC4 Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102837G2, MC4 Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102837G3, MC4 Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005912
• UniProt ID: P32245
• Synonyms: MGC126851; MGC138197
• Summary: The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010]