Human Eph receptor A4 (EPHA4) activation kit by CRISPRa

CAT#: GA101422

EPHA4 CRISPRa kit - CRISPR gene activation of human EPH receptor A4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: EPHA4
• Locus ID: 2043
• Kit Components:

  GA101422G1, Eph receptor A4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101422G2, Eph receptor A4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101422G3, Eph receptor A4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001304536, NM_001304537, NM_004438, NM_001363748
• UniProt ID: P54764
• Synonyms: HEK8; SEK; TYRO1
• Summary: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]