Human LFA3 (CD58) activation kit by CRISPRa

CAT#: GA100686

CD58 CRISPRa kit - CRISPR gene activation of human CD58 molecule

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CD58
• Locus ID: 965
• Kit Components:

  GA100686G1, LFA3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100686G2, LFA3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100686G3, LFA3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001144822, NM_001779, NR_026665
• UniProt ID: P19256
• Synonyms: ag3; LFA-3; LFA3
• Summary: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]