Human NAT2 activation kit by CRISPRa

CAT#: GA100004

NAT2 CRISPRa kit - CRISPR gene activation of human N-acetyltransferase 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: NAT2
• Locus ID: 10
• Kit Components:

  GA100004G1, NAT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100004G2, NAT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100004G3, NAT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000015
• UniProt ID: P11245
• Synonyms: AAC2; NAT-2; PNAT
• Summary: This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second polymorphic arylamine N-acetyltransferase gene (NAT1), is located near this gene (NAT2). [provided by RefSeq, Sep 2019]