Arntl (NM_024362) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR210481L3V

Lenti ORF particles, Arntl (Myc-DDK-tagged ORF) - Rat aryl hydrocarbon receptor nuclear translocator-like (Arntl), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Arntl
• Synonyms: Bmal1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_024362
• ORF Size: 1878 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR210481).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_024362.2, NP_077338.2
• RefSeq Size: 2991 bp
• RefSeq ORF: 1881 bp
• Locus ID: 29657
• UniProt ID: Q9EPW1
• Cytogenetics: 1q33
• Gene Summary: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with Clock. This heterodimer binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. [provided by RefSeq, Jan 2014]