SFRP1 (NM_003012) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC207328L2V
- LentiORF®
Lenti ORF particles, SFRP1 (mGFP-tagged) - Human secreted frizzled-related protein 1 (SFRP1), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP w/ Puro
AAV Particle: DDK
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USD 365.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | SFRP1 |
Synonyms | FRP; FRP-1; FRP1; FrzA; SARP2 |
Mammalian Cell Selection | None |
Vector | pLenti-C-mGFP |
ACCN | NM_003012 |
ORF Size | 942 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207328).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_003012.3 |
RefSeq Size | 4465 bp |
RefSeq ORF | 945 bp |
Locus ID | 6422 |
UniProt ID | Q8N474 |
Cytogenetics | 8p11.21 |
Domains | FRI, NTR |
Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway, Transmembrane |
Protein Pathways | Wnt signaling pathway |
MW | 35.2 kDa |
Gene Summary | This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009] |
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