Dll4 (NM_019454) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR212151L3V

Lenti ORF particles, Dll4 (Myc-DDK-tagged) - Mouse delta-like 4 (Drosophila) (Dll4), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Dll4
• Synonyms: Delta4
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_019454
• ORF Size: 2058 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR212151).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019454.2, NP_062327.1
• RefSeq Size: 3426 bp
• RefSeq ORF: 2061 bp
• Locus ID: 54485
• UniProt ID: Q9JI71
• Cytogenetics: 2 E5
• Gene Summary: Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (By similarity). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (PubMed:22323600). During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity).[UniProtKB/Swiss-Prot Function]