Stk36 (BC043103) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR211549L4V

Lenti ORF particles, Stk36 (GFP-tagged) - Mouse serine/threonine kinase 36 (fused homolog, Drosophila) (cDNA clone MGC:58023 IMAGE:6406485), complete, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Stk36
• Synonyms: FU, MGC58023, B930045J24
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: BC043103
• ORF Size: 3159 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR211549).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: BC043103.1
• RefSeq Size: 3378 bp
• RefSeq ORF: 3161 bp
• Locus ID: 269209
• Cytogenetics: 1 C4
• Gene Summary: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia.[UniProtKB/Swiss-Prot Function]