PER3 (NM_001289864) Human Untagged Clone

CAT#: SC337638

PER3 (untagged) - Human period circadian clock 3 (PER3), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PER3
• Synonyms: FASPS3; GIG13
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001289864, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTTGCCATACACCAAAAAGTTTTGAAGTATGCAGGGCATCCTCCCTTTGAACATTCTCCCATTCGAT
  TTTGTACTCAAAACGGAGACTACATCATACTGGATTCCAGTTGGTCCAGCTTTGTGAATCCCTGGAGCCG
  GAAGATTTCTTTCATCATTGGTCGGCATAAAGTTCGAACGAGCCCACTAAATGAGGATGTTTTTGCTACC
  AAAATTAAAAAGATGAACGATAATGACAAAGACATAACAGAATTACAAGAACAAATTTACAAACTTCTCT
  TACAGCCAGTTCACGTGAGCGTGTCCAGCGGCTACGGGAGCCTGGGGAGCAGCGGGTCGCAGGAGCAGCT
  TGTCAGCATCGCCTCCTCCAGTGAGGCCAGTGGGCACCGTGTGGAGGAGACGAAGGCGGAGCAGATGACC
  TTGCAGCAGGTCTATGCCAGTGTGAACAAAATTAAAAATCTGGGTCAGCAGCTCTACATTGAGTCAATGA
  CCAAATCATCATTCAAGCCAGTGACGGGGACACGCACAGAACCGAATGGTGGTGGTGAGTCAGCGAATGG
  TGGTGGTGAATGTAAGACCTTTACTTCCTTCCACCAAACACTGAAAAACAATAGTGTGTACACTGAGCCC
  TGTGAGGATTTGAGGAACGATGAGCACAGCCCATCCTATCAACAGATCAACTGTATCGACAGTGTCATCA
  GATACCTGAAGAGCTACAACATTCCAGCTTTGAAAAGAAAGTGTATCTCCTGTACAAATACAACTTCTTC
  CTCCTCAGAAGAAGACAAACAGAACCACAAGGCAGATGATGTCCAAGCCTTACAAGCTGGTTTGCAAATC
  CCAGCCATACCTAAATCAGAAATGCCAACAAATGGACGGTCCATAGACACAGGAGGAGGAGCTCCACAGA
  TCCTGTCCACGGCGATGCTGAGCTTGGGGTCGGGCATAAGCCAATGCGGTTACAGCAGCACCATTGTCCA
  TGTCCCACCCCCAGAGACAGCCAGGGATGCTACCCTCTTCTGTGAGCCCTGGACCCTGAACATGCAGCCA
  GCCCCTTTGACCTCGGAAGAATTTAAACACGTGGGGCTCACAGCGGCTGTTCTGTCAGCGCACACCCAGA
  AGGAAGAGCAGAATTATGTTGATAAATTCCGAGAAAAGATCCTGTCATCACCCTACAGCTCCTATCTTCA
  GCAAGAAAGCAGGAGCAAAGCTAAATATTCATATTTTCAAGGAGATTCTACTTCCAAGCAGACGCGGTCG
  GCCGGCTGCAGGAAAGGGAAGCACAAGCGGAAGAAGCTGCCGGAGCCGCCAGACAGCAGCAGCTCGAACA
  CCGGCTCTGGTCCCCGCAGGGGAGCGCATCAGAACGCACAGCCCTGCTGCCCCTCCGCGGCCTCCTCTCC
  GCACACCTCGAGCCCGACCTTCCCACCTGCCGCCATGGTGCCCAGCCAGGCCCCTTACCTCGTCCCAGCT
  TTTCCCCTCCCAGCCGCGACCTCACCCGGAAGAGAATACGCAGCCCCCGGAACTGCACCGGAAGGCCTGC
  ATGGGCTGCCCTTGTCCGAGGGCTTGCAGCCTTACCCAGCTTTCCCTTTTCCTTACTTGGATACTTTTAT
  GACCGTTTTCCTGCCTGACCCCCCTGTCTGTCCTCTGTTGTCGCCATCGTTTTTGCCATGTCCATTCCTG
  GGGGCGACAGCCTCTTCTGCGATATCACCCTCAATGTCGTCAGCAATGAGTCCAACTCTGGACCCACCCC
  CTTCAGTCACCAGCCAAAGGAGAGAGGAGGAAAAGTGGGAGGCACAAAGCGAGGGGCACCCGTTCATTAC
  TTCGAGAAGCAGCTCACCCTTGCAGTTAAACTTACTTCAGGAAGAGATGCCCAGACCCTCTGAATCTCCA
  GATCAGATGAGAAGGAACACGTGCCCACAAACTGAGTATTGTGTTACAGGCAACAATGGCAGTGAGAGCA
  GTCCTGCTACTACCGGTGCACTGTCCACGGGGTCACCTCCCAGGGAGAATCCATCCCATCCTACTGCCAG
  CGCTCTGTCCACAGGATCGCCTCCCATGAAGAATCCATCCCATCCTACTGCCAGCGCTCTGTCCACAGGA
  TCGCCTCCCATGAAGAATCCATCCCATCCTACTGCCAGCACACTGTCCATGGGATTGCCTCCCAGCAGGA
  CTCCATCCCATCCTACTGCCACTGTTCTGTCCACGGGGTCACCTCCCAGCGAATCCCCATCCAGAACTGG
  TTCAGCAGCATCAGGAAGCAGCGACAGCAGTATATACCTTACTAGTAGTGTTTATTCTTCTAAAATCTCC
  CAAAATGGGCAGCAATCTCAGGACGTACAGAAAAAAGAAACATTTCCTAATGTCGCCGAAGAGCCCATCT
  GGAGAATGATACGGCAGACACCTGAGCGCATTCTCATGACATACCAGGTACCTGAGAGGGTTAAAGAAGT
  TGTACTAAAAGAAGACCTGGAAAAGCTAGAAAGTATGAGGCAGCAGCAGCCCCAGTTTTCTCATGGGCAA
  AAGGAGGAGCTGGCTAAGGTGTATAATTGGATTCAAAGCCAGACTGTCACTCAAGAAATCGACATTCAAG
  CCTGTGTCACTTGTGAAAATGAAGATTCAGCTGATGGTGCGGCCACATCCTGTGGTCAGGTTCTGGTAGA
  AGACAGCTGTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001289864
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001289864.1, NP_001276793.1
• RefSeq Size: 6394 bp
• RefSeq ORF: 2673 bp
• Locus ID: 8863
• UniProt ID: P56645
• Cytogenetics: 1p36.23
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Circadian rhythm - mammal
• Gene Summary: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]
  Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence and uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (5) is shorter at the N-terminus and lacks a single internal aa compared to isoform 1.