GRO beta (CXCL2) (NM_002089) Human Untagged Clone

CAT#: SC320418

CXCL2 (untagged)-Human chemokine (C-X-C motif) ligand 2 (CXCL2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GRO beta
• Synonyms: CINC-2a; GRO2; GROb; MGSA-b; MIP-2a; MIP2; MIP2A; SCYB2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002089 edited
  GCCACAGGCAGCTCCTTGCCAGCTCTCCTCCTCGCACAGCCGCTCGAACCGCCTGCTGAG
  CCCCATGGCCCGCGCCACGCTCTCCGCCGCCCCCAGCAATCCCCGGCTCCTGCGGGTGGC
  GCTGCTGCTCCTGCTCCTGGTGGCCGCCAGCCGGCGCGCAGCAGGAGCGCCCCTGGCCAC
  TGAACTGCGCTGCCAGTGCTTGCAGACCCTGCAGGGAATTCACCTCAAGAACATCCAAAG
  TGTGAAGGTGAAGTCCCCCGGACCCCACTGCGCCCAAACCGAAGTCATAGCCACACTCAA
  GAATGGGCAGAAAGCTTGTCTCAACCCCGCATCGCCCATGGTTAAGAAAATCATCGAAAA
  GATGCTGAAAAATGGCAAATCCAACTGACCAGAAGGAAGGAGGAAGCTTATTGGTGGCTG
  TTCCTGAAGGAGGCCCTGCCCTTACAGGAACAGAAGAGGAAAGAGAGACACAGCTGCAGA
  GGCCACCTGGATTGCGCCTAATGTGTTTGAGCATCACTTAGGAGAAGTCTTCTATTTATT
  TATTTATTTATTTATTTATTTGTTTGTTTTAGAAGATTCTATGTTAATATTTTATGTGTA
  AAATAAGGTTATGATTGAATCTACTTGCACACTCTCCCATTATATTTATTGTTTATTTTA
  GGTCAAACCCAAGTTAGTTCAATCCTGATTCATATTTAATTTGAAGATAGAAGGTTTGCA
  GATATTCTCTAGTCATTTGTTAATATTTCTTCGTGATGACATATCACATGTCAGCCACTG
  TGATAGAGGCTGAGGAATCCAAGAAAATGGCCAGTAAGATCAATGTGACGGCAGGGAAAT
  GTATGTGTGTCTATTTTGTAACTGTAAAGATGAATGTCAGTTGTTATTTATTGAAATGAT
  TTCACAGTGTGTGGTCAACATTTCTCATGTTGAAGCTTTAAGAACTAAAATGTTCTAAAT
  ATCCCTTGGACATTTTATGTCTTTCTTGTAAGGCATACTGCCTTGTTTAATGTTAATTAT
  GCAGTGTTTCCCTCTGTGTTAGAGCAGAGAGGTTTCGATATTTATTGATGTTTTCACAAA
  GAACAGGAAAATAAAATATTTAAAAATAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_002089
• Insert Size: 1100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002089.1, NP_002080.1
• RefSeq Size: 1110 bp
• RefSeq ORF: 324 bp
• Locus ID: 2920
• UniProt ID: P19875
• Cytogenetics: 4q13.3
• Domains: IL8
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway
• Gene Summary: This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]