Leukotriene B4 Receptor (LTB4R) (NM_181657) Human Untagged Clone

CAT#: SC319120

LTB4R (untagged)-Human leukotriene B4 receptor (LTB4R), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Leukotriene B4 Receptor
• Synonyms: BLT1; BLTR; CMKRL1; GPR16; LTB4R1; LTBR1; P2RY7; P2Y7
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_181657.1 CTCTCTCACTGCTCCTTCCTGGTCTCTTCTCATCTGGCCCCACCTCTAAGGAGTCCTCCT
  GCCTTCTGGGTTGCCCTGGAAAACAGACTATCCCCCCTCCTAGTGAAGGGAGTGGGTAGG
  GGTTTCAGCCCCACCCTCAGGAAGATGCGTCTTCCCTGTCCTCTGCTCTGTGGTACTTCC
  TCTCTGGCTGATTTAGCAAACAGCACCTAGACCTGGGGCCAGGCCTTTGGCAGTGGGACA
  GATCCAGGGATAGGCTACACCACCCTGCCCTGACCCTGGGATTGGCATCAGCTTCCAACC
  AGTTCCTGCCAAAGCTTGTCCTCCCGACGGCCATGAACACTACATCTTCTGCAGCACCCC
  CCTCACTAGGTGTAGAGTTCATCTCTCTGCTGGCTATCATCCTGCTGTCAGTGGCGCTGG
  CTGTGGGGCTTCCCGGCAACAGCTTTGTGGTGTGGAGTATCCTGAAAAGGATGCAGAAGC
  GCTCTGTCACTGCCCTGATGGTGCTGAACCTGGCCCTGGCCGACCTGGCCGTATTGCTCA
  CTGCTCCCTTTTTCCTTCACTTCCTGGCCCAAGGCACCTGGAGTTTTGGACTGGCTGGTT
  GCCGCCTGTGTCACTATGTCTGCGGAGTCAGCATGTACGCCAGCGTCCTGCTTATCACGG
  CCATGAGTCTAGACCGCTCACTGGCGGTGGCCCGCCCCTTTGTGTCCCAGAAGCTACGCA
  CCAAGGCGATGGCCCGGCGGGTGCTGGCAGGCATCTGGGTGTTGTCCTTTCTGCTGGCCA
  CACCCGTCCTCGCGTACCGCACAGTAGTGCCCTGGAAAACGAACATGAGCCTGTGCTTCC
  CGCGGTACCCCAGCGAAGGGCACCGGGCCTTCCATCTAATCTTCGAGGCTGTCACGGGCT
  TCCTGCTGCCCTTCCTGGCTGTGGTGGCCAGCTACTCGGACATAGGGCGTCGGCTACAGG
  CCCGGCGCTTCCGCCGCAGCCGCCGCACCGGCCGCCTGGTGGTGCTCATCATCCTGACCT
  TCGCCGCCTTCTGGCTGCCCTACCACGTGGTGAACCTGGCTGAGGCGGGCCGCGCGCTGG
  CCGGCCAGGCCGCCGGGTTAGGGCTCGTGGGGAAGCGGCTGAGCCTGGCCCGCAACGTGC
  TCATCGCACTCGCCTTCCTGAGCAGCAGCGTGAACCCCGTGCTGTACGCGTGCGCCGGCG
  GCGGCCTGCTGCGCTCGGCGGGCGTGGGCTTCGTCGCCAAGCTGCTGGAGGGCACGGGCT
  CCGAGGCGTCCAGCACGCGCCGCGGGGGCAGCCTGGGCCAGACCGCTAGGAGCGGCCCCG
  CCGCTTTGGAGCCCGGCCCTTCCGAGAGCCTCACTGCCTCCAGCCCTTTCAAGTTAAACG
  AACTGAACTAGGCCTGGTGGAAGGAGGCGCACTTTCCTCCTGGCAGAATGCTAGCTCTGA
  GCCAGTTCAGTACCTGGAGGAGGAGCAGGGGCGTGGAGGGCGTGGAGGGCGTGGGAGCGT
  GGGAGGCGGGAGTGGAGTGGAAGAAGAGGGAGAGATGGAGCAAAGTGAGGGCCGAGTGAG
  AGCGTGCTCCAGCCTGGCTCCCACAGGCAGCTTTAACCATTAAAACTGAAGTCTGAAATT
  TGAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_181657
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_181657.1, NP_858043.1
• RefSeq Size: 3023 bp
• RefSeq ORF: 1059 bp
• Locus ID: 1241
• UniProt ID: Q15722
• Cytogenetics: 14q12
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer transcript. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.