BAMBI (NM_012342) Human Untagged Clone

CAT#: SC115396

BAMBI (untagged)-Human BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) (BAMBI)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BAMBI
• Synonyms: NMA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115396 sequence for NM_012342 edited (data generated by NextGen Sequencing)
  ATGGATCGCCACTCCAGCTACATCTTCATCTGGCTGCAGCTGGAGCTCTGCGCCATGGCC
  GTGCTGCTCACCAAAGGTGAAATTCGATGCTACTGTGATGCTGCCCACTGTGTAGCCACT
  GGTTATATGTGTAAATCTGAGCTCAGCGCCTGCTTCTCTAGACTTCTTGATCCTCAGAAC
  TCAAATTCCCCACTCACCCATGGCTGCCTGGACTCTCTTGCAAGCACGACAGACATCTGC
  CAAGCCAAACAGGCCCGAAACCACTCTGGCACCACCATACCCACATTGGAATGCTGTCAT
  GAAGACATGTGCAATTACAGAGGGCTGCACGATGTTCTCTCTCCTCCCAGGGGTGAGGCC
  TCAGGACAAGGAAACAGGTATCAGCATGATGGTAGCAGAAACCTTATCACCAAGGTGCAG
  GAGCTGACTTCTTCCAAAGAGTTGTGGTTCCGGGCAGCGGTCATTGCCGTGCCCATTGCT
  GGAGGGCTGATTTTAGTGTTGCTTATTATGTTGGCCCTGAGGATGCTTCGAAGTGAAAAT
  AAGAGGCTGCAGGATCAGCGGCAACAGATGCTCTCCCGTTTGCACTACAGCTTTCACGGA
  CACCATTCCAAAAAGGGGCAGGTTGCAAAGTTAGACTTGGAATGCATGGTGCCGGTCAGT
  GGGCACGAGAACTGCTGTCTGACCTGTGATAAAATGAGACAAGCAGACCTCAGCAACGAT
  AAGATCCTCTCGCTTGTTCACTGGGGCATGTACAGTGGGCACGGGAAGCTGGAATTCGTA
  TGA
  
  Clone variation with respect to NM_012342.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012342 unedited
  TTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGAGAGAGAGAGAG
  AACTGGGCTGGCGCGGGCGGGAGCTGCGGCGGATACCCTTGCGTGCTGTGGAGACCCTAC
  TCTCTTCGCTGAGAACGGCCGCTAGCGGGGACTGAAGGCCGGGAGCCCACTCCCGACCCG
  GGGCTAGCGTGCGTCCCTAGAGTCGAGCGGGGCAAGGGAGCCAGTGGCCGCCGACGGGGG
  ACCGGGAAACTTTTCTGGGCTCCTGGGCGCGCCCTGTAGCCGCGCTCCATGCTCCGGCAG
  CGGCCCGAAACCCAGCCCCGCCGCTGACGGCGCCCGCCGCTCCGGGCAGGGCCCATGCCC
  TGCGCGCTCCGGGGGTCGTAGGCTGCCGCCGAGCCGGGGCTCCGGAAGCCGGCGGGGGCG
  CCGCGGCCGTGCGGGGCGTCAATGGATCGCCACTCCAGCTACATCTTCATCTGGCTGCAG
  CTGGAGCTCTGCGCCATGGCCGTGCTGCTCACCAAAGGTGAAATTCGATGCTACTGTGAT
  GCTGCCCACTGTGTAGCCACTGGTTATATGTGTAAATCTGAGCTCAGCGCCTGCTTCTCT
  AGACTTCTTGATCCTCAGAACTCAAATTCCCCACTCACCCATGGCTGCCTGGACTCTCTT
  GCAAGCACGACAGACATCTGCCAAGCCAAACAGGCCCGAAACCACTCTGGCACCACCATA
  CCCACATTGGAATGCTGTCATGAAGACATGTGCCATTACAGAGGGCTGCACGATGTTCTC
  TCTCCTCCAGGGGTGATGCCTCAGGACAAGGAACCAGTATCACCATGATGTTAGCAGAAA
  CTTATCACCAGTGCAAGAGCTGACTCCTCCAAGAAGTGGTGGTCCGGGCAGCGGTCATTG
  CCGGCCCATG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012342 unedited
  GTCGGAGCTCCGCCTGCGGGGNNCGAGAAAAAACTTTTCTTTTTTGGTGGTTAGTTGGTT
  TTTTTTTCTTTTTTGGGGGGAGGCATACACATTGGAAAAGTATTCCGGAACACCTGGATC
  AAAATGACCTTTGCTAGGTCAACTCCAGAAATTGATCAATCATATCTGACCTGGTACACA
  TAAATTCCAGATCTCCTTCTTAAATGAAGTCCATACCAGAGTTATCCTATAGCCAGAATG
  GGGGTAAGACACTAAAAGATGGGCAGTATACATTTAGAAACTCCACACTGTAAGAAAATT
  ACACAGGCACATGGAAGAATAAGCAAGATCTTGGTCTTGTTTAAAAAAGAAAAGAGAAAA
  AAAAAAACCAAGCCACATCCTAGAGTTGAGAACAAATTATTAACAGCAAATGGCCATTTG
  TATAATTAACATGTACTGTCTCACGTTTCCCAGTTAAATTTATGAAAGACACTATTAAAT
  TTCAGACAAAATATATATATCCCTTTTAAATCTTTACAATAAATCAAGATGTAGAAGCTC
  ACATAGGGCACATTTTTGCTTATTTAGGTACTCAATTCCAGCTCCCTTGGATGCAAATAA
  CCCTGGGGACAGTGGGCACAAAGGCTTCTCTTTGCTTTTTATAATTTTAAAGCAAATAAC
  ACATTTAACTGCATTTAAGCCTGTGCCAAAAATCCCTTCAGAGGAAACATCCAAGAATCT
  GGTCGCAGAGGTCACTTTGTCTCTCAAAGATGATTAAAAGAGCTTGGCCACCAAAAAAGG
  GGCTCTGGCCAGCCAAACTCACAAGGCCTCCAAGCTGTCCAGTAAGGGGAGTTCAAATAG
  ACTCCGTCATAGAAATCCCAGTCCCGGGCCCCTGTCCTGCCCCATGAACACCGAGAGAAC
  TTACCGCGCTGAGCCGGCCTGCCAATTAAACAGAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012342
• Insert Size: 2190 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012342.2, NP_036474.1
• RefSeq Size: 1732 bp
• RefSeq ORF: 783 bp
• Locus ID: 25805
• UniProt ID: Q13145
• Cytogenetics: 10p12.1
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]