HLA-DOA Rabbit Polyclonal Antibody

CAT#: TA358899

HLA-DOA Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: DOA Sample Type: MDA-MB-435s Whole Cell lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DOA
• Specificity: Expected reactivity: Cow, Horse, Human, Pig, Rat
  Homology: Cow: 83%; Horse: 85%; Human: 100%; Pig: 86%; Rat: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 27kDa
• Gene Name: major histocompatibility complex, class II, DO alpha
• Database Link:
  NP_002110
  Entrez Gene 3111 Human
  UniProt ID P06340
• Background: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.