MEKK2 (MAP3K2) Rabbit Polyclonal Antibody

CAT#: TA350774

Rabbit Polyclonal Anti-MAP3K2 Antibody

Product Images

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (MAP3K2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

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  The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using (MAP3K2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ELISA: 1000-2000, IHC: 25-100
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human MAP3K2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mitogen-activated protein kinase kinase kinase 2
• Database Link:
  NP_006600
  Entrez Gene 26405 MouseEntrez Gene 10746 Human
  UniProt ID Q9Y2U5
• Background: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
• Synonyms: MEKK2; MEKK2B

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Gap junction, GnRH signaling pathway, MAPK signaling pathway