Fc epsilon RI (FCER1A) Rabbit Polyclonal Antibody

CAT#: TA327164

Rabbit anti-FCER1A Polyclonal Antibody

Product Images

Western blot analysis of extracts of mouse spleen cell lines, using FCER1A antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human FCER1A
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Fc fragment of IgE receptor Ia
• Database Link:
  NP_001992
  Entrez Gene 2205 Human
  UniProt ID P12319
• Background: Fc fragment of IgE, high affinity I, receptor for, alpha polypeptide, also known as high affinity immunoglobulin epsilon receptor subunit alpha, FCER1A and FCE1A, is a single-pass type I membrane protein which contains 2 immunoglobulin-like domains. FCER1A is a subunit of the IgE receptor, which is composed of one glycosylated alpha (FCER1A), one beta (FCER1B), and two gamma (FCER1G) subunits. The high affinity IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.
• Synonyms: FCE1A; FcERI

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Asthma, Fc epsilon RI signaling pathway