ABCG2 Mouse Monoclonal Antibody [Clone ID: 1H2]
Other products for "ABCG2"
Specifications
Product Data | |
Clone Name | 1H2 |
Applications | ELISA, IF, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. |
Reactivities | Human, Monkey, Mouse |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human ABCG2 expressed in E. Coli. |
Specificity | This antibody recognizes ABCG2. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 72 kDa |
Gene Name | ATP binding cassette subfamily G member 2 (Junior blood group) |
Database Link | |
Background | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon. |
Synonyms | Breast cancer resistance protein 1, ABCP, MXR |
Reference Data |
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