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- Druggable Genome
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Category
Target Symbol
- MEK1 (11)
- P21 RAS (6)
- ALDH1L1 (4)
- ATP5F1B (4)
- BCAR1 (4)
- CHK2 (4)
- JNK2 (4)
- PP5 (4)
- PROTEASOME SUBUNIT ALPHA TYPE 6 (4)
- BETA CATENIN (3)
- C-JUN (3)
- DPP9 (3)
- FH (3)
- HSP60 (3)
- MEK3 (3)
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- ACBD3 (2)
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- GLUTATHIONE SYNTHETASE (2)
- GRF2 (2)
- HSP75 (2)
- LIPOAMIDE DEHYDROGENASE (2)
- NPTN (2)
- PACSIN3 (2)
- PHOSPHORIBOSYL PYROPHOSPHATE AMIDOTRANSFERASE (2)
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- PROTEIN C INHIBITOR (2)
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- TRAP ALPHA (2)
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- AIPL1 (1)
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- PROTEASOME 20S BETA 7 (1)
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- TPMT (1)
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- TULP3 (1)
- UBIQUINOL CYTOCHROME C REDUCTASE CORE PROTEIN I (1)
- USP13 (1)
- USP36 (1)
Antibody Hosts
Clonalities
Conjugates
Knockout (KO) Validation
Pathways
- MAPK signaling pathway (36)
- Focal adhesion (34)
- Pathways in cancer (34)
- Neurotrophin signaling pathway (32)
- GnRH signaling pathway (31)
- T cell receptor signaling pathway (29)
- Fc epsilon RI signaling pathway (28)
- Insulin signaling pathway (27)
- Renal cell carcinoma (27)
- ErbB signaling pathway (26)
- Toll-like receptor signaling pathway (25)
- B cell receptor signaling pathway (24)
- Endometrial cancer (23)
- Regulation of actin cytoskeleton (23)
- Thyroid cancer (23)
- Chemokine signaling pathway (22)
- Colorectal cancer (22)
- Melanogenesis (22)
- Prostate cancer (22)
- Metabolic pathways (21)
- VEGF signaling pathway (21)
- Bladder cancer (20)
- Melanoma (20)
- Acute myeloid leukemia (19)
- Chronic myeloid leukemia (19)
- Gap junction (19)
- Glioma (19)
- Long-term depression (19)
- Long-term potentiation (19)
- Natural killer cell mediated cytotoxicity (19)
- Non-small cell lung cancer (19)
- Progesterone-mediated oocyte maturation (18)
- Pancreatic cancer (16)
- Prion diseases (13)
- Vascular smooth muscle contraction (13)
- Dorso-ventral axis formation (12)
- Fc gamma R-mediated phagocytosis (12)
- Oocyte meiosis (12)
- Wnt signaling pathway (10)
- Epithelial cell signaling in Helicobacter pylori infection (9)
- Leukocyte transendothelial migration (9)
- Tight junction (9)
- Axon guidance (8)
- Endocytosis (8)
- Alzheimer's disease (7)
- Huntington's disease (7)
- NOD-like receptor signaling pathway (7)
- Proteasome (7)
- RIG-I-like receptor signaling pathway (6)
- Adherens junction (5)
- Amyotrophic lateral sclerosis (ALS) (5)
- Cell cycle (5)
- Citrate cycle (TCA cycle) (5)
- Oxidative phosphorylation (5)
- Parkinson's disease (5)
- Type II diabetes mellitus (5)
- Adipocytokine signaling pathway (4)
- Basal cell carcinoma (4)
- One carbon pool by folate (4)
- Pathogenic Escherichia coli infection (4)
- Purine metabolism (4)
- p53 signaling pathway (4)
- Alanine (3)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (3)
- Complement and coagulation cascades (3)
- RNA degradation (3)
- Type I diabetes mellitus (3)
- Valine (3)
- aspartate and glutamate metabolism (3)
- leucine and isoleucine degradation (3)
- Apoptosis (2)
- Cardiac muscle contraction (2)
- Cell adhesion molecules (CAMs) (2)
- Glutathione metabolism (2)
- Glycine (2)
- Glycolysis / Gluconeogenesis (2)
- Hematopoietic cell lineage (2)
- Lysosome (2)
- Pyruvate metabolism (2)
- serine and threonine metabolism (2)
- Amino sugar and nucleotide sugar metabolism (1)
- Arachidonic acid metabolism (1)
- Arginine and proline metabolism (1)
- Basal transcription factors (1)
- Base excision repair (1)
- Biosynthesis of unsaturated fatty acids (1)
- DNA replication (1)
- Dilated cardiomyopathy (1)
- Drug metabolism - other enzymes (1)
- ECM-receptor interaction (1)
- Fatty acid elongation in mitochondria (1)
- Glycerolipid metabolism (1)
- Glycerophospholipid metabolism (1)
- Hedgehog signaling pathway (1)
- Hypertrophic cardiomyopathy (HCM) (1)
- Mismatch repair (1)
- Nucleotide excision repair (1)
- Phosphatidylinositol signaling system (1)
- Pyrimidine metabolism (1)
- TGF-beta signaling pathway (1)
- Vibrio cholerae infection (1)
- mTOR signaling pathway (1)