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Target Symbol
- ALK (15)
- MEK1 (12)
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- BETA CATENIN (10)
- NM23A (10)
- PI 3 KINASE CLASS 2A (10)
- GEPHYRIN (9)
- PCNA (9)
- RAB37 (9)
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- CDK2 (7)
- GADD45G (7)
- GTP CYCLOHYDROLASE 1 (7)
- HADHSC (7)
- HER2 (7)
- NANP (7)
- ORNITHINE CARBAMOYLTRANSFERASE (7)
- RHOJ (7)
- SNAP25 (7)
- THYMIDYLATE SYNTHASE (7)
- AMDHD1 (6)
- AP2M1 (6)
- ARL3 (6)
- FGFR2 (6)
- GROWTH ARREST SPECIFIC PROTEIN 7 (6)
- MACRO H2A.2 (6)
- PI 3 KINASE CATALYTIC SUBUNIT GAMMA (6)
- SELENIUM BINDING PROTEIN 1 (6)
- TUBB2B (6)
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- AKR1A1 (5)
- AMYLOID PRECURSOR PROTEIN (5)
- AREB6 (5)
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- CYTOKERATIN 16 (5)
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Antibody Hosts
Knockout (KO) Validation
Assay Types
Families
- Druggable Genome (761)
- Transcription Factors (188)
- Transmembrane (148)
- Protein Kinase (146)
- ES Cell Differentiation/IPS (78)
- Protease (60)
- Stem cell - Pluripotency (58)
- Secreted Protein (45)
- Phosphatase (25)
- Nuclear Hormone Receptor (18)
- Embryonic stem cells (12)
- Adult stem cells (11)
- Stem cell relevant signaling - DSL/Notch pathway (9)
- Cancer stem cells (5)
- Ion Channels: Other (5)
- P450 (5)
- Stem cell relevant signaling - JAK/STAT signaling pathway (5)
- GPCR (4)
- Stem cell relevant signaling - Wnt Signaling pathway (4)
- Induced pluripotent stem cells (3)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (2)
Pathways
- Metabolic pathways (177)
- Pathways in cancer (115)
- MAPK signaling pathway (101)
- Prostate cancer (80)
- Focal adhesion (75)
- Colorectal cancer (63)
- Insulin signaling pathway (62)
- Progesterone-mediated oocyte maturation (60)
- Endometrial cancer (56)
- ErbB signaling pathway (56)
- Pancreatic cancer (53)
- Regulation of actin cytoskeleton (53)
- Fc epsilon RI signaling pathway (52)
- Acute myeloid leukemia (51)
- Toll-like receptor signaling pathway (49)
- B cell receptor signaling pathway (48)
- Chronic myeloid leukemia (48)
- Glioma (47)
- Gap junction (46)
- Neurotrophin signaling pathway (46)
- Non-small cell lung cancer (45)
- Melanoma (43)
- VEGF signaling pathway (43)
- Cell cycle (42)
- GnRH signaling pathway (41)
- T cell receptor signaling pathway (41)
- Natural killer cell mediated cytotoxicity (40)
- Renal cell carcinoma (40)
- Wnt signaling pathway (39)
- Bladder cancer (38)
- Oocyte meiosis (38)
- Pyrimidine metabolism (38)
- Chemokine signaling pathway (36)
- Fc gamma R-mediated phagocytosis (36)
- Thyroid cancer (36)
- Purine metabolism (35)
- Melanogenesis (34)
- Pathogenic Escherichia coli infection (34)
- Type II diabetes mellitus (33)
- Ubiquitin mediated proteolysis (31)
- Adherens junction (30)
- Small cell lung cancer (30)
- Long-term potentiation (29)
- Leukocyte transendothelial migration (28)
- Long-term depression (28)
- mTOR signaling pathway (28)
- Vascular smooth muscle contraction (27)
- Alzheimer's disease (25)
- Apoptosis (25)
- Endocytosis (25)
- Parkinson's disease (23)
- Phosphatidylinositol signaling system (23)
- Amyotrophic lateral sclerosis (ALS) (22)
- Inositol phosphate metabolism (22)
- Jak-STAT signaling pathway (22)
- Proteasome (22)
- Axon guidance (20)
- Adipocytokine signaling pathway (19)
- Basal cell carcinoma (19)
- Hedgehog signaling pathway (19)
- Prion diseases (19)
- Arginine and proline metabolism (18)
- Calcium signaling pathway (18)
- Huntington's disease (18)
- Nucleotide excision repair (18)
- Tight junction (18)
- p53 signaling pathway (18)
- Base excision repair (17)
- Glycolysis / Gluconeogenesis (17)
- DNA replication (16)
- Dorso-ventral axis formation (16)
- Epithelial cell signaling in Helicobacter pylori infection (16)
- Mismatch repair (15)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (14)
- Cytokine-cytokine receptor interaction (13)
- TGF-beta signaling pathway (13)
- Lysine degradation (12)
- Valine (12)
- leucine and isoleucine degradation (12)
- Butanoate metabolism (11)
- Dilated cardiomyopathy (11)
- Hypertrophic cardiomyopathy (HCM) (11)
- NOD-like receptor signaling pathway (11)
- Notch signaling pathway (11)
- One carbon pool by folate (11)
- Arachidonic acid metabolism (10)
- SNARE interactions in vesicular transport (10)
- Spliceosome (10)
- Amino sugar and nucleotide sugar metabolism (9)
- Drug metabolism - cytochrome P450 (9)
- Fatty acid metabolism (9)
- Glutathione metabolism (9)
- Histidine metabolism (9)
- Oxidative phosphorylation (9)
- RNA degradation (9)
- Regulation of autophagy (9)
- Systemic lupus erythematosus (9)
- Terpenoid backbone biosynthesis (9)
- Tryptophan metabolism (9)
- ABC transporters (8)
- Alanine (8)
- Antigen processing and presentation (8)
- Maturity onset diabetes of the young (8)
- Metabolism of xenobiotics by cytochrome P450 (8)
- Primary immunodeficiency (8)
- Pyruvate metabolism (8)
- Vibrio cholerae infection (8)
- aspartate and glutamate metabolism (8)
- Cardiac muscle contraction (7)
- Cell adhesion molecules (CAMs) (7)
- Fatty acid elongation in mitochondria (7)
- Folate biosynthesis (7)
- Glycine (7)
- RNA polymerase (7)
- serine and threonine metabolism (7)
- Cysteine and methionine metabolism (6)
- Glycerolipid metabolism (6)
- Glycerophospholipid metabolism (6)
- Porphyrin and chlorophyll metabolism (6)
- RIG-I-like receptor signaling pathway (6)
- Propanoate metabolism (5)
- beta-Alanine metabolism (5)
- Glycosphingolipid biosynthesis - lacto and neolacto series (4)
- Keratan sulfate biosynthesis (4)
- N-Glycan biosynthesis (4)
- Ribosome (4)
- Starch and sucrose metabolism (4)
- Viral myocarditis (4)
- Ascorbate and aldarate metabolism (3)
- Circadian rhythm - mammal (3)
- Complement and coagulation cascades (3)
- Drug metabolism - other enzymes (3)
- Nicotinate and nicotinamide metabolism (3)
- Pantothenate and CoA biosynthesis (3)
- Renin-angiotensin system (3)
- Retinol metabolism (3)
- Type I diabetes mellitus (3)
- Tyrosine metabolism (3)
- Vitamin B6 metabolism (3)
- Cytosolic DNA-sensing pathway (2)
- ECM-receptor interaction (2)
- Fructose and mannose metabolism (2)
- Hematopoietic cell lineage (2)
- Lysosome (2)
- Methane metabolism (2)
- Neuroactive ligand-receptor interaction (2)
- Nitrogen metabolism (2)
- PPAR signaling pathway (2)
- Synthesis and degradation of ketone bodies (2)
- Taste transduction (2)
- Caffeine metabolism (1)
- Citrate cycle (TCA cycle) (1)
- Cyanoamino acid metabolism (1)
- D-Glutamine and D-glutamate metabolism (1)
- Ether lipid metabolism (1)
- Glycosaminoglycan degradation (1)
- Glyoxylate and dicarboxylate metabolism (1)
- Homologous recombination (1)
- Linoleic acid metabolism (1)
- Non-homologous end-joining (1)
- Other glycan degradation (1)
- Pentose phosphate pathway (1)
- Phenylalanine (1)
- Phenylalanine metabolism (1)
- Primary bile acid biosynthesis (1)
- Sphingolipid metabolism (1)
- Steroid biosynthesis (1)
- Taurine and hypotaurine metabolism (1)
- Thiamine metabolism (1)
- Ubiquinone and other terpenoid-quinone biosynthesis (1)
- alpha-Linolenic acid metabolism (1)
- tyrosine and tryptophan biosynthesis (1)