LIN28B (NM_001004317) Human Recombinant Protein
CAT#: TP760648
Purified recombinant protein of Human lin-28 homolog B (C. elegans) (LIN28B), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length LIN28B
|
Tag | N-His |
Predicted MW | 26.9 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 20 mM PB, pH 7.4 |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001004317 |
Locus ID | 389421 |
UniProt ID | Q6ZN17 |
Cytogenetics | 6q16.3-q21 |
Refseq Size | 5504 |
Refseq ORF | 750 |
Synonyms | CSDD2 |
Summary | The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012] |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC424091 | LIN28B HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY424091 | Transient overexpression lysate of lin-28 homolog B (C. elegans) (LIN28B) |
USD 436.00 |
|
TP761960 | Purified recombinant protein of Human lin-28 homolog B (C. elegans) (LIN28B),full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug |
USD 261.00 |
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