Dectin 1 (CLEC7A) (NM_197950) Human Recombinant Protein
CAT#: TP760392
Purified recombinant protein of Human C-type lectin domain family 7, member A (CLEC7A), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length CLEC7A
|
Tag | N-His |
Predicted MW | 19 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_922941 |
Locus ID | 64581 |
UniProt ID | Q9BXN2, Q68D78 |
Cytogenetics | 12p13.2 |
Refseq Size | 2355 |
Refseq ORF | 504 |
Synonyms | BGR; CANDF4; CD369; CLECSF12; DECTIN1; SCARE2 |
Summary | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transmembrane |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC405148 | CLEC7A HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC405151 | CLEC7A HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC405152 | CLEC7A HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC430694 | CLEC7A HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY405148 | Transient overexpression lysate of C-type lectin domain family 7, member A (CLEC7A), transcript variant 1 |
USD 436.00 |
|
LY405151 | Transient overexpression lysate of C-type lectin domain family 7, member A (CLEC7A), transcript variant 5 |
USD 436.00 |
|
LY405152 | Transient overexpression lysate of C-type lectin domain family 7, member A (CLEC7A), transcript variant 6 |
USD 436.00 |
{0} Product Review(s)
Be the first one to submit a review