Desmin (DES) (NM_001927) Human Recombinant Protein
CAT#: TP760253
Recombinant protein of human desmin (DES), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length DES
|
Tag | N-His |
Predicted MW | 53.4 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001918 |
Locus ID | 1674 |
UniProt ID | P17661, Q53SB5 |
Cytogenetics | 2q35 |
Refseq Size | 2268 |
Refseq ORF | 1410 |
Synonyms | CDCD3; CSM1; CSM2; LGMD1D; LGMD1E; LGMD2R |
Summary | This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400713 | DES HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY400713 | Transient overexpression lysate of desmin (DES) |
USD 436.00 |
|
TP720562 | Recombinant protein of human desmin (DES) |
USD 330.00 |
|
TP761590 | Purified recombinant protein of Human desmin (DES), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug |
USD 261.00 |
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