Cd38 Mouse Recombinant Protein
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Specifications
Product Data | |
Species | Mouse |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Leu45-Thr304
|
Tag | C-His |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
Note | Recombinant Mouse ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1 is produced by our Mammalian expression system and the target gene encoding Leu45-Thr304 is expressed with a 6His tag at the C-terminus. |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 12494 |
UniProt ID | P56528 |
Summary | CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a Signal-anchor for type II membrane protein. CD38 is able to transform NAD+ to ADP-D-ribose and nicotinamide. It also can transform NADP+ to nicotinate-adenine dinucleotide phosphate and nicotinamide. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.