Aurora A (AURKA) Human Recombinant Protein

CAT#: TP725658

Recombinant Human AuroraA (122-403, N-His)

Specifications

Product Data

• Species: Human
• Protein Source: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Glu122-Ser403
• Tag: N-6His
• Buffer: Supplied as a 0.2 um filtered solution of 50mM Tris, 100mM NaCl, 10%glycerol, 1mM DTT, pH7.4
• Note: Recombinant Human AuroraA (122-403) is produced by our mammalian expression system and the target gene encoding Glu122-Ser403 is expressed with a His tag at the N terminus.
• Storage: Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 6790
• UniProt ID: O14965
• Synonyms: AIK; AIKAurA; ARK1; ARK-1; AURA; AURKA; Aurora A; aurora kinase AhARK1
• Summary: AuroraA is a part of the protein kinase superfamily. AuroraA is a serine/threonine kinase that contributes to the regualtion of cell cycle progression while also playing critical roles in various mitotic events like cytokinesis. This protein is required for both the intitation of activating CDK1 at the centrosomes and normal axon formation. AuroraA also phosphorylates its own inhibitors to inhibit their activity.
• Protein Families: Druggable Genome, Protein Kinase, Stem cell - Pluripotency
• Protein Pathways: Oocyte meiosis