PR3 (PRTN3) Human Recombinant Protein

CAT#: TP725312

Recombinant Human Proteinase 3/Myeloblastin (C-His)

Specifications

Product Data

• Species: Human
• Protein Source: Human 293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Ala26-Arg249
• Tag: C-6His
• Buffer: Supplied as a 0.2 um filtered solution of 10mM TrisHCl, 150mM NaCl, 10% Glycerol, pH8.0
• Note: Recombinant Human Proteinase 3 is produced by our Mammalian expression system and the target gene encoding Ala26-Arg249 is expressed with a 6His tag at the C-terminus.
• Storage: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 5657
• UniProt ID: P24158
• Summary: Myeloblastin, also known as Human Proteinase 3 is a member of the peptidase S1 family. This protein is expressed by both monocytes and neutrophils, the neutrophils secretes, isolates in azurophilic granules, or expresses Myeloblastin on the cell's surface. When the Myeloblastin is secreted, it activates the kinin pathway and when isolated it aids in digestion of phagocytosed material.