TRIM5 alpha (TRIM5) (NM_033092) Human Recombinant Protein
CAT#: TP721169M
Purified recombinant protein of Human tripartite motif containing 5 (TRIM5), transcript variant gamma
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Gln248
|
Tag | N-His |
Predicted MW | 30.8 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_149083 |
Locus ID | 85363 |
UniProt ID | Q9C035 |
Cytogenetics | 11p15.4 |
Refseq Size | 3659 |
Refseq ORF | 1041 |
Synonyms | RNF88; TRIM5alpha |
Summary | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009] |
Protein Families | Druggable Genome |
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