UBE2V1 (TMEM189-UBE2V1) (NM_199203) Human Recombinant Protein

CAT#: TP720973L

Purified recombinant protein of Human TMEM189-UBE2V1 readthrough (TMEM189-UBE2V1)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Ala2-Asn147
• Tag: C-His
• Predicted MW: 17.5 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 um filtered solution of 50mM HEPES, 100mM NaCl, pH 8.0.
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_954673
• Locus ID: 387522
• UniProt ID: Q13404, A5PLL7
• Cytogenetics: 20q13.13
• Refseq Size: 2852
• Refseq ORF: 1110
• Synonyms: CROC-1B; CROC1B; KUA-UEV; TMEM189-UBE2V1
• Summary: The TMEM189-UEV mRNA is an infrequent but naturally occurring read-through transcript of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this read-through mRNA and the function of its protein product has not yet been determined. [provided by RefSeq, Oct 2010]
• Protein Families: Transmembrane