AGR3 (NM_176813) Human Recombinant Protein
CAT#: TP720456XL
Recombinant protein of human anterior gradient homolog 3 (Xenopus laevis) (AGR3)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Ile22-Leu166
|
Tag | C-His |
Predicted MW | 18.1 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM EDTA, pH 8.5. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_789783 |
Locus ID | 155465 |
UniProt ID | Q8TD06 |
Cytogenetics | 7p21.1 |
Synonyms | AG-3; AG3; BCMP11; hAG-3; HAG3; PDIA18 |
Summary | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016] |
Protein Families | Secreted Protein |
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