IL17F (NM_052872) Human Recombinant Protein
CAT#: TP720022M
Recombinant protein of human interleukin 17F (IL17F)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Arg31-Gln163
|
Tag | Tag Free |
Predicted MW | 15 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mMPB,pH7.4. |
Bioactivity | ED50 is approximately 10 ng/ml as determined by the dose-dependent induction of IL-6 in NIH-3T3 cells. Specific Activity of 1.0 x 105 IU/mg |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_443104 |
Locus ID | 112744 |
UniProt ID | Q96PD4, Q6NSI0 |
Cytogenetics | 6p12.2 |
Synonyms | CANDF6; IL-17F; ML-1; ML1 |
Summary | The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Secreted Protein |
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