Complex IV subunit Va (42-150, His-tag) Human Protein
CAT#: AR50691PU-N
Complex IV subunit Va (42-150, His-tag) human recombinant protein, 0.5 mg
Size: 100 ug
Other products for "COX5A"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSSHGSQET DEEFDARWVT YFNKPDIDAW ELRKGINTLV TYDMVPEPKI IDAALRACRR LNDFASTVRI LEVVKDKAGP HKEIYPYVIQ ELRPTLNELG ISTPEELGLD KV
|
Tag | His-tag |
Predicted MW | 14.9 kDa |
Concentration | lot specific |
Purity | >95% by SDS - PAGE |
Presentation | Purified |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 2 mM DTT |
Preparation | Liquid purified protein |
Protein Description | Recombinant human COX5A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_004246 |
Locus ID | 9377 |
UniProt ID | P20674 |
Cytogenetics | 15q24.2 |
Synonyms | COX; COX-VA; MC4DN20; VA |
Summary | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008] |
Protein Pathways | Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
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