Sp7 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN316514BN

Sp7 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: Sp7
• Locus ID: 170574
• Components:

  KN316514G1, Sp7 gRNA vector 1 in pCas-Guide CRISPR vector

  KN316514G2, Sp7 gRNA vector 2 in pCas-Guide CRISPR vector

  KN316514BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_130458, NM_001348205
• UniProt ID: Q8VI67
• Synonyms: 6430578P22Rik; C22; Osx
• Summary: Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences.[UniProtKB/Swiss-Prot Function]