Jag1 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN308537RB

Jag1 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: Jag1
• Locus ID: 16449
• Components:

  KN308537G1, Jag1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN308537G2, Jag1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN308537RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_013822
• UniProt ID: Q9QXX0
• Synonyms: ABE2; Gsfabe2; Htu; Ozz; Ser-1
• Summary: Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). May regulate fibroblast growth factor-induced angiogenesis.[UniProtKB/Swiss-Prot Function]