Apobec3 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN301413LP
Apobec3 - mouse gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
USD 450.00
USD 686.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | Apobec3 |
Locus ID | 80287 |
Components |
KN301413G1, Apobec3 gRNA vector 1 in pCas-Guide CRISPR vector KN301413G2, Apobec3 gRNA vector 2 in pCas-Guide CRISPR vector KN301413LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001160415, NM_001347041, NM_030255 |
UniProt ID | Q99J72 |
Synonyms | Apobec; Arp3; BC003314; Cem15; Rfv3 |
Summary | DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against HIV-1, simian immunodeficiency viruses (SIVs), mouse mammary tumor virus (MMTV) and friend murine leukemia virus (FrMLV) and may inhibit the mobility of LTR retrotransposons.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN301413 | Apobec3 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN301413BN | Apobec3 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN301413RB | Apobec3 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN501413 | Apobec3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
|
GA211109 | Apobec3 CRISPRa kit - CRISPR gene activation of mouse apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 |
USD 1,657.00 |
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