PLK5 Human Gene Knockout Kit (CRISPR)

CAT#: KN233808BN

PLK5 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: PLK5
• Locus ID: 126520
• Components:

  KN233808G1, PLK5 gRNA vector 1 in pCas-Guide CRISPR vector

  KN233808G2, PLK5 gRNA vector 2 in pCas-Guide CRISPR vector

  KN233808BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001011716, NM_001243079, NR_026557
• UniProt ID: Q496M5
• Synonyms: PLK-5; PLK5P; SgK384ps
• Summary: Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.[UniProtKB/Swiss-Prot Function]