DLL1 Human Gene Knockout Kit (CRISPR)

CAT#: KN222399LP

DLL1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: DLL1
• Locus ID: 28514
• Components:

  KN222399G1, DLL1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN222399G2, DLL1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN222399LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_005618
• UniProt ID: O00548
• Synonyms: Delta; DELTA1; DL1
• Summary: DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]