Argonaute 2 (AGO2) Human Gene Knockout Kit (CRISPR)

CAT#: KN218078RB

AGO2 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: Argonaute 2
• Locus ID: 27161
• Components:

  KN218078G1, Argonaute 2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN218078G2, Argonaute 2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN218078RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001164623, NM_012154
• UniProt ID: Q9UKV8
• Synonyms: EIF2C2; Q10
• Summary: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]