Orexin Receptor 1 (HCRTR1) Human Gene Knockout Kit (CRISPR)

CAT#: KN210381LP

HCRTR1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: Orexin Receptor 1
• Locus ID: 3061
• Components:

  KN210381G1, Orexin Receptor 1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN210381G2, Orexin Receptor 1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN210381LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001525
• UniProt ID: O43613
• Synonyms: OX1R
• Summary: The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009]