DNA Ligase III (LIG3) Human Gene Knockout Kit (CRISPR)
CAT#: KN209530RB
LIG3 - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro Luciferase-Puro mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
USD 450.00
USD 1,317.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | DNA Ligase III |
Locus ID | 3980 |
Components |
KN209530G1, DNA Ligase III gRNA vector 1 in pCas-Guide CRISPR vector KN209530G2, DNA Ligase III gRNA vector 2 in pCas-Guide CRISPR vector KN209530RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_002311, NM_013975 |
UniProt ID | P49916 |
Synonyms | LIG2 |
Summary | This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN209530 | LIG3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN209530BN | LIG3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN209530LP | LIG3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN409530 | LIG3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
|
GA102695 | LIG3 CRISPRa kit - CRISPR gene activation of human DNA ligase 3 |
USD 1,657.00 |
{0} Product Review(s)
Be the first one to submit a review