AP2 gamma (TFAP2C) Human Gene Knockout Kit (CRISPR)

CAT#: KN208665LP

TFAP2C - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: AP2 gamma
• Locus ID: 7022
• Components:

  KN208665G1, AP2 gamma gRNA vector 1 in pCas-Guide CRISPR vector

  KN208665G2, AP2 gamma gRNA vector 2 in pCas-Guide CRISPR vector

  KN208665LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_003222
• UniProt ID: Q92754
• Synonyms: AP2-GAMMA; ERF1; hAP-2g; TFAP2G
• Summary: The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq, Jul 2008]