RAMP2 Human Gene Knockout Kit (CRISPR)
CAT#: KN206531LP
RAMP2 - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
USD 450.00
USD 450.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | RAMP2 |
Locus ID | 10266 |
Components |
KN206531G1, RAMP2 gRNA vector 1 in pCas-Guide CRISPR vector KN206531G2, RAMP2 gRNA vector 2 in pCas-Guide CRISPR vector KN206531LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_005854 |
UniProt ID | O60895 |
Summary | The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq, Jul 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN206531 | RAMP2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN206531BN | RAMP2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN206531RB | RAMP2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN406531 | RAMP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA106990 | RAMP2 CRISPRa kit - CRISPR gene activation of human receptor activity modifying protein 2 |
USD 1,657.00 |
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